After the events of Full Frontal Assault, Ratchet and Clank are patrolling the Polaris Galaxy in Aphelion. However, do to a technical mishap involving an Omega-Class Quantum Equalizer, the ship's thrusters cut and Aphelion, Ratchet, and Clank are sucked into a Black Hole and are sent flying down a wormhole.
The wormhole spits the trio out into orbit around planet Zeldrin. Originally the wormhole sends them catapulting towards the Zeldrin Starport, but due to Ratchet's quick engagement of Aphelion's Thrustmaster 500, he and Clank manage to dock safely. Shortly after discovering that they are in the Solana Galaxy, the Starport comes under attack by a strange unknown Warship which emerged from the wormhole shortly after the Aphelion. Inter-starship bridges slam into the Starport. Their doors open, allowing the Starship's boarding parties to invade. The Station's defense forces moblize against the attackers, and Ratchet assists them. After the bulk of the boarding party is defeated, the remaining forces retreat back into the Warship. Clank then realizes that the invaders were Megacorp Extermibots, which he and Ratchet had encountered before on planet Damosel of the Bogon Galaxy. They wonder why Megacorp would be attacking an incosiqentual Starport in the Solana Galaxy, so they decide to head to Megacorp's headquarters on Damosel to find some answers. However, unlike Ratchet's previous Star Explorer, Aphelion is not equipped with a Grav-O-Metric Warp Drive, which is needed to traverse galaxies, so, instead, the duo heads to the Starship Pheonix, were Big Al was located.